What anti-aging skincare products do dermatologists recommend?
I’ll give you a hint: you apply them before your moisturizer but after you cleanse.
I’m talking about the best anti-aging serums for women in their 50s.
A lot of people don’t know that women over 50 need a special serum made specifically for mature skin. The ingredients are great for maintaining skin elasticity and strength which is crucial for skincare at this age.
The issue is that a lot of skincare products on the market today are of poor quality. That’s why we decided to do these reviews, to give you the best options to help maintain healthy skin in your 50s and beyond.
Here’s the Best Anti Aging Serum for 50s (2023 Update)
1. Eve Hansen Anti-Aging Serum Set
If you’re new to serums, this set with three bottles is perfect for experimenting to find what works best for you.
It contains hyaluronic acid, vitamin C, and retinol serums.
Each one is made with botanic and organic ingredients. To illustrate, the retinol serum features organic green tea, jojoba, aloe, and vitamins A and E. It erases fine lines and minimizes wrinkles because it encourages the renewal of your skin at a cellular level.
Next, the vitamin C serum brightens skin tone and diminishes age spots. It neutralizes free radicals from pollution and UV radiation that cause premature aging (1).
Finally, the hyaluronic acid serum provides essential moisture to plump and soften the skin.
None of the above contain parabens.
2. Boots No7 Protect & Perfect Intense Advanced Anti-Aging Serum
Peptides are clinically proven to rejuvenate mature skin. Specifically, this serum contains Matrixyl 3000 Plus, a next-generation peptide formula with antioxidants.
Within two weeks of daily use, you’ll notice that your skin looks great. After four weeks, fine lines and wrinkles are noticeably smaller. And since you can keep using this skincare product continuously, it just keeps getting better.
3. InstaNatural Retinol Serum
There’s one problem with retinol: it tends to cause dryness and flaking. It may sting when you first apply it.
But InstaNatural’s retinol serum is a best selling American-made product that comes with a 100% satisfaction guarantee.
It’s rich in hydrating ingredients like aloe, licorice root, and niacinamide to defend against dryness and leave your skin radiant and moisturized.
Moreover, it includes Vitamin C and hyaluronic acid to ensure you have everything you need to turn back time.
4. Vitamin C Serum by L’Oreal Paris
L’Oreal’s serum has a 10% concentration of pure Vitamin C.
Since this ingredient tends to degrade when exposed to sunlight and oxygen, they’ve packaged it in a metal tube without water and with nitrogen to keep it stable for as long as possible.
With only one week of using it, you’ll notice a positive difference. Even the first time you apply it you’ll see that it’s a perfect primer for underneath makeup. It leaves your skin like satin.
If you have sensitive skin, you’ll be glad to know it’s tested to be hypoallergenic plus it’s free of parabens and artificial dyes.
5. Hyaluronic Acid Serum by L’Oreal Paris Skincare
L’Oreal also makes a hyaluronic acid serum that visibly hydrates dry skin and fades fine lines and wrinkles.
It’s free of artificial fragrances, dyes, and parabens.
What makes this particular serum stand out when compared to other similar skincare products? It has a 1.5% concentration of pure hyaluronic acid with both high and low molecular weights. In other words, it moisturizes both the surface and deep underneath.
6. CeraVe Anti-Aging Retinol Serum
CeraVe encapsulates retinol in something they call the MVE, or MultiVehicular Emulsion. This prevents the retinol from degrading and helps it sink deeper into the skin.
The formula also includes three essential ceramides that reinforce the skin’s natural barrier against moisture loss.
Like other skincare products from the same company, it’s made to be gentle for sensitive skin, and it’s free of artificial fragrances.
7. InstaNatural Niacinamide 5% Face Serum
With all the focus on Vitamin C and retinol, it’s easy to miss the benefits of niacinamide. It’s vitamin B3 that is naturally hydrating for irritated skin.
This potent ingredient reduces redness and blotchiness; it lightens dark spots and clears up blemishes. It also improves elasticity while fighting fine lines and wrinkles.
InstaNatural includes hyaluronic acid and other moisturizers in this serum as well.
8. RoC Retinol Correxion Deep Wrinkle Facial Serum
RoC makes one of the best-selling serums on the market. It’s proven to firm the skin noticeably in only four weeks. Within twelve weeks, even deep wrinkles are less apparent.
If you would prefer to avoid cosmetic procedures, try this product first. While it can’t replace chemical peels or Botox injections, it can improve your appearance to a significant degree.
The serum absorbs quickly so that you can apply makeup over the top. Just be sure to wear sunscreen as retinol sensitizes the skin to sunlight.
9. COOLA Organic Sunless Tan Anti-Aging Face Serum
If you’re concerned about the chemicals you use on your skin, you’ll appreciate this serum. It will help you look bronzed without the risks of tanning.
COOLA uses organic ingredients certified by ECOCERT COSMOS, plus it’s vegan and reef-friendly.
It has antioxidants and vitamins as well as hyaluronic acid and argan oil to moisturize and nourish the skin. Additionally, the natural piña colada scent makes it feel like you’re on vacation when you apply it.
10. KLEEM Vitamin C Serum for Face with 25% Vitamin C, 10% Hyaluronic Acid & Vitamin E
KLEEM also favors organic ingredients for their Vitamin C serum. It comes with a 100% money-back guarantee see you can try it with low risk.
Vitamin C is a favorite anti-aging remedy. It removes age spots and restores suppleness.
As an antioxidant, it defends against photo-aging and inflammation (2).
11. Hada Labo Tokyo Anti-Aging Hydrator
This Japanese serum provides an intense dose of hyaluronic acid along with retinol and collagen. First, it improves the appearance of your complexion on the surface as soon as you smooth it on the skin.
Second, it sinks in deeper to firm and renew tissue underneath.
Users say it leaves their face velvety soft and creates the perfect canvas for applying foundation.
Also, it’s free of parabens and perfumes.
12. Aveeno Absolutely Ageless Intensive Anti-Aging Renewal Serum
Aveeno hasn’t abandoned oat extract. It’s still the primary ingredient in many of their skincare products. Instead, they’ve expanded their lineup with a blackberry complex.
They say that you’ll see smoother skin with only a week of daily use.
On the downside, this formula contains an artificial fragrance. Worse, blackberry appears to be the second to last ingredient on the label.
13. CLARINS Double Serum Anti-aging
CLARINS includes twenty plant extracts into their Double Serum. Some of those include turmeric, oats, and avocado.
Ninety percent of the women surveyed who used it were happier with it over the serum they had tried before.
14. It Cosmetics No 50 Serum Anti-Aging Collagen Veil Primer
Are you wishing for one product that does it all? IT Cosmetics packs fifty anti-aging components into this serum.
Go ahead, read the label. It lists peptides, niacin, collagen, lipids, vitamins, and botanical extracts, among other things.
It shrinks pores, as well as smooths fine lines and wrinkles. Regular use firms the skin and fight free radicals.
Users say it has the consistency of light cream. It takes a few minutes to absorb but isn’t greasy.
15. Skin Beauty Solutions C E Ferulic
Chances are when you begin to learn about anti-aging serums, you’ll hear about this one. This is one of the best for mature skin.
Skin Beauty Solutions blends Vitamin C and E plus ferulic acid for maximum benefits. It neutralizes the damage caused by ozone, air pollution, infrared, and UV radiation. These sources cause the skin to dry out and get fine lines and wrinkles prematurely.
But the serum rehydrates, brightens, and firms.
If you’ve just had laser surgery done, this is a product that’s designed to be safe for post-procedure care.
16. Body Merry Super 6 Anti-Aging Serum
Body Merry incorporates hyaluronic acid, Coenzyme Q10, niacinamide, retinol, Astaxanthin, and 22% Vitamin C into their serum. It also features witch hazel, jojoba oil, organic green tea, aloe, and dandelion extract.
As you can guess, it perks up both skin tone and texture so that you only need one product, not two or three.
The company offers a ninety-day manufacturer guarantee to ensure your satisfaction.
17. Elizabeth Arden PREVAGE Anti-Aging Daily Serum
The PREVAGE serum treats signs of aging caused by pollution, too much sun, and smoke. It corrects dryness and discoloration while it diminishes wrinkles. It can also fade redness and scars.
18. Paula’s Choice RESIST Anti-Aging Omega+ Complex Serum
Paula’s Choice employs superfoods to feed your skin back to health. Their skincare formula includes passionfruit, Chia seed, olive oil, and flaxseed. Together, they moisturize, strengthen the skin, reduce inflammation and redness, and soften wrinkles.
Take the time to read the label, and you’ll discover something rare. They explain the purpose of every single ingredient. They leave out irritants like parabens and it’s fragrance free.
19. Face Serum with Collagen Peptide by Olay Regenerist
Olay’s Regenerist serum promises results within two weeks. You might even notice firmer skin after only five days.
It’s created to lessen wrinkles on dry, normal, combination, or oily skin. The fact that it has mica in it makes your complexion luminous, but not glittery.
Some of the key ingredients include peptides, carob extract, hyaluronic acid, niacinamide, and tea leaf.
20. La Roche-Posay Redermic R Serum
The Redermic R serum has won awards for its ability to halt premature aging. It’s an anti-wrinkle moisturizer for underneath your makeup.
Boosters like adenosine and retinyl linoleate aid retinol in rejuvenating the skin. At the same time, lipo-hydroxy acid exfoliates to reveal fresh, clear skin underneath.
Those with sensitive skin (like rosacea) take note: the label lists a fragrance, salicylic acid, and phenoxyethanol.
A note about rosacea: if you have chronic redness on your face and chest, ask your doctor if it’s rosacea. You may also notice small pimples that resemble acne.
This condition is very common among women in their 40s and 50s. It’s sometimes mistaken for flushing linked to menopause.
But if you have rosacea, it makes it more difficult to select the best serum for your skin. Stick to mild skincare products to see how you react.
21. La Roche-Posay Substiane Serum Visible Density & Volume Replenishing Corrector
As we age, our skin loses hydration and looks dull. But the Substiane serum restores density and suppleness. It revives mature skin so that it feels more comfortable and looks distinctly younger.
The subtle decoration of the bottle disguises the 21st-century technology inside. The serum uses successful lab-designed molecules like Pro-Xylane, Linactyl, and LR 2412 to fix the skin beyond what “natural” ingredients can do.
What’s the Difference Between a Serum and a Moisturizer?
A serum has a compact molecular structure that penetrates deeper than a moisturizer can into the skin.
It’s concentrated and designed to treat specific issues and fight free radicals.
For example, you might use one with retinol to enhance collagen production and smooth wrinkles.
Since there are many different kinds, which serum is best for aging skin?
In general, those with Vitamin C, retinol, and hyaluronic acid meet the hydration requirements of mature skin.
How to Get the Most out of Your Face Serum
Once you wash with a mild cleanser (like these ones) and leave the skin damp, spread two or three drops on your face.
Give it a few minutes to sink in, then apply your moisturizer and makeup as usual.
For best results, apply a serum both morning and night.
Be aware that it can take four to eight weeks to see a noticeable difference with hydration.
Now let’s get to the best face serum reviews to help you find the ones you need.
Do Anti-Aging Serums Really Work?
Yes, science shows that anti-aging serums improve mature skin (3).
They are efficient because they are super-concentrated and they reach deeper layers of the skin than an ordinary moisturizer can.
Women with oily skin find that serums are very convenient. They sink in without making the face greasy. A serum feels weightless, but it moisturizes and tightens the skin in preparation for makeup on top.
Then, women with dry skin discover that a serum provides the extra hydration boost they need.
Related: Best anti aging supplements reviewed
We hope you decided to add an anti-aging serum to your skincare routine today. Within a few weeks, you’ll witness significant improvements.
We’d love to know about your experience. Please leave us a comment below to tell us which serum you’re using and what it’s done for you.
1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699641/ Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety by Siddharth Mukherjee, et al., published December 2006, accessed 06 June 2019
2. https://www.livescience.com/36720-anti-aging-products-lotions-supplements.html by Linda Thrasybule, published November 5, 2012, accessed June 06, 2019
3. https://www.webmd.com/beauty/features/beauty-smarts-serums-jan13#1 by Shelley Levitt, published October 2012, accessed June 06, 2019
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